Centella Asiatica (Gotukola) Mouthwash as an Adjunct to Mechanical Plaque Control

Sri Hasanamba Dental College and Hospital

Status and phase: Completed; Phase 1

Conditions: Gingival Diseases

Treatments: Drug: Gotukola; Procedure: Scaling

Study type: Interventional

Funder types: Other

Identifiers

NCT02827305

SHDCH/2015-16/1409

Details and patient eligibility

About

This study evaluates the adjunctive use of Centella Asiatica (gotukola) to scaling in the reduction of plaque and gingival inflammation. Patients were divided into three groups of which group 1 received scaling and gotukola mouthwash, group 2 received scaling only and group 3 received gotukola mouthwash only.

Full description

Mechanical plaque control by tooth brushing is considered to be the ideal way of preventing plaque associated gingivitis. However due to various factors individuals fail to perform an adequate quality of self performed plaque control. Centella Asiatica (gotukola) possess wide range of biological activities like anti-inflammatory, anti-psoriatic, anti-ulcer, hepato-protective, anticonvulsant, immunostimulant, cardioprotective, antidiabetic, antiviral, antibacterial, antifungal, etc. So, it could be used as adjunctive to mechanical periodontal therapy.

Enrollment: 36 patients

Sex: All

Ages: 14 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Minimum of 22 natural teeth
• Participants with Chronic generalized gingivitis
• Participants with plaque index score ≥1

Exclusion criteria

• Participants with fixed or removable appliances
• Participants with more than full coverage restorations
• Medically compromised participants
• Participants on long term medications
• Smokers
• Participants who had used any type of antibacterial mouthwash in 4weeks of commencement.
• Patients with history of recent periodontal therapy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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36 participants in 3 patient groups

group 1

Experimental group

Description:

scaling and Gotukola mouthwash intervention- 1.Scaling 2.Gotukola mouthwash , 10ml twice daily to be rinsed for 60 seconds

Treatment:

Procedure: Scaling

Drug: Gotukola

group 2

Active Comparator group

Description:

Scaling

Treatment:

Procedure: Scaling

group 3

Active Comparator group

Description:

Intervention- Gotukola mouthwash only is advised to be used two times a day, each time 10ml rinsed for 60 seconds (morning and evening ) after the food.

Treatment:

Drug: Gotukola