Central and Peripheral Arterial Pressure Decoupling In Cardio-Pulmonary Bypass (CAPD-CPB)

Civil Hospices of Lyon

Status: Completed

Conditions: Cardiac Surgery; Cardiopulmonary Bypass; Extracorporeal Circulation

Treatments: Procedure: Non-invasive blood pressure oscillometer (NIBP) implementation

Study type: Interventional

Funder types: Other

Identifiers

NCT02652858

69HCL15_0400

Details and patient eligibility

About

Central and peripheral arterial pressure decoupling occurs in some clinical conditions like sepsis or cardiopulmonary bypass. This decoupling may leed to unsuitable decisions such as the use of catecholamines.

The aim of this study is to evaluate the pulse wave's speed as a marker of central and peripheral arterial pressure decoupling in a scheduled condition which is the cardiopulmonary bypass during cardiac surgery.

Enrollment: 40 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Scheduled patient for coronary or valvular surgery with cardiopulmonary bypass
• Cardiopulmonary bypass is at least 90 minutes
• Written consent is needed

Exclusion criteria

• Patient with heart rate disorder
• Patient with aortic dissection
• Dobutamine/milrinone/levosimendan treatment before surgery
• Patient with heart rate due to a pacemaker

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

Pulse wave's speed observational arm

Experimental group

Description:

Whole patients for who the pulse wave's speed are measured during a cardiopulmonary bypass during cardiac surgery

Treatment:

Procedure: Non-invasive blood pressure oscillometer (NIBP) implementation