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Central Corneal Thickness in Glaucoma

A

Aristotle University Of Thessaloniki

Status

Completed

Conditions

Exfoliation Syndrome

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

The purpose of this study is to compare the central corneal thickness measurement in patients with exfoliation syndrome, exfoliative glaucoma, primary open-angle glaucoma, ocular hypertension and normal controls and to evaluate the value of corneal thickness in the diagnosis and management of glaucoma.

Full description

To compare the central corneal thickness measurement in patients with exfoliation, primary open-angle glaucoma, ocular hypertension and normal controls and to evaluate the value of corneal thickness in the diagnosis and management of glaucoma. Prospective study in progress. Randomly selected patients undergo a comprehensive ophthalmic exam which includes 2 separate pachymetry measurements in 2 different examinations at the same time of the day (10:00 am) with 3 different pachymeters. The values obtained are correlated with a number of other glaucoma parameters. A thinner cornea may represent a specific attribute and an additional risk factor for patients with exfoliation. Evaluation of corneal thickness is an important exam in the management of patients with exfoliation.

Enrollment

700 patients

Sex

All

Ages

25 to 89 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Exfoliation material on pupil
  • Intraocular pressure below 21 mm Hg without glaucomatous damage
  • Intraocular pressure above 21 mm Hg without glaucomatous damage
  • Raised intraocular pressure with glaucomatous damage

Exclusion criteria

  • Corneal disorders
  • History of trauma
  • Evidence of corneal abnormality that may influence IOP
  • Contact lens use
  • Corneal surgery

Trial design

700 participants in 4 patient groups

primary open-angle glaucoma
ocular hypertension patients
normal controls
Exfoliation patients
Description:
patients with exfoliation syndrome or exfoliative glaucoma

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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