Central Hemodynamics

Luzerner Kantonsspital

Status: Unknown

Conditions: Hypertension

Treatments: Other: Optimization of blood pressure according to guidelines

Study type: Observational

Funder types: Other

Identifiers

NCT01837784

13024

Details and patient eligibility

About

Guidelines recommend measuring end organ damage and in particular arterial stiffness in patients with hypertension. However, until now it was not possible to measure arterial stiffness with the use of simple methods. Recently, novel and innovative devices offering determination of arterial stiffness and central hemodynamics from simple and non-invasive arm cuff measurements have now become available. This study therefore evaluates the value of non-invasively measured arterial stiffness and central hemodynamics for guiding antihypertensive treatment in selected patient populations (i.e. elderly patients, patients with diabetes mellitus, patients with heart failure, and patients with resistant hypertension).

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients >70 years (elderly cohort)
• Patients with diabetes mellitus (diabetes cohort)
• Patients with heart failure (heart failure cohort)
• Patients with resistant hypertension (resistant hypertension cohort)

Exclusion criteria

• Patient refuses study participation
• Severe renal failure
• Reduced life expectancy

Trial design

100 participants in 4 patient groups

Elderly patients

Treatment:

Other: Optimization of blood pressure according to guidelines

Patients with diabetes mellitus

Treatment:

Other: Optimization of blood pressure according to guidelines

Patients with heart failure

Treatment:

Other: Optimization of blood pressure according to guidelines

Patients with resistant hypertension

Treatment:

Other: Optimization of blood pressure according to guidelines