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Central Sensitization in Knee Osteoarthritis

Ç

Çukurova University

Status

Completed

Conditions

Central Sensitisation
Osteo Arthritis Knee

Treatments

Other: balance exercises

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

The stimuli that activate nociceptors cause the dorsal horn of the spinal cord neurons to be sensitive to low-intensive afferent stimuli by decreasing the excitation threshold in patients with osteoarthritis. Although painful stimuli disappear, this situation causes pain to continue and a decrease in quality of life. Therefore, central sensitization should be considered and treated in patients with osteoarthritis. Although various pharmacological and electrophysiological agents are used in the treatment of central sensitization, adequate efficacy is not provided in patients with osteoarthritis. The aim of this study is to investigate the effects of balance exercises on central sensitization in patients with knee osteoarthritis.

Enrollment

40 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Being diagnosed with primary knee osteoarthritis according to American College of Rheumatology criteria,
  • To be stage 2-3-4 knee osteoarthritis according to Kellgren Lawrence radiological staging,
  • To be with a central sensitization score of over 40 according to the CSI,
  • To be able to fill the scales and accept to participate in the study.

Exclusion criteria

  • Being diagnosed with secondary osteoarthritis or inflammatory rheumatic disease,
  • Having cognitive impairment,
  • To have been treated with physiotherapy, with an intra articular injection or with a surgery from the knee within a maximum of six months
  • Having various diseases that may adversely affect performing balance exercises,

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

40 participants in 2 patient groups

Balance exercises and information
Experimental group
Description:
Balance exercises six weeks and three days in a week and information about central sensitisation.
Treatment:
Other: balance exercises
Information
No Intervention group
Description:
Information about central sensitisation.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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