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Centralized Cord Blood Registry to Facilitate Unrelated Cord Blood Transplantation

N

National Marrow Donor Program (NMDP)

Status and phase

Completed
Phase 2

Conditions

Lymphoma
Leukemia
Myelodysplastic Syndromes

Treatments

Biological: HPC, Cord Blood

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

The National Marrow Donor Program (NMDP) has established a system for registering, matching, and tracking unrelated donor cord blood units (CBUs) and transplant outcomes. Study subjects are donors who enroll through collaborating cord blood banks. This study creates uniform collection, screening, testing and storage requirements for cord blood units. The purpose of standardization is to improve efficiency in the selection of cord blood units for transplantation.

Full description

The NMDP Cord Blood registry is organized as a network of member cord blood banks and transplant centers whose interactions are managed by the NMDP's Center for Cord Blood. Banks agree to comply with uniform collection, screening, testing and storage requirements. Upon approval of membership, cord blood banks submit detailed information on each stored CBU for registration into a proprietary computer system. A transplant center, working on behalf of potential recipients, submits search requests to the NMDP and receives electronic reports detailing potentially suitable CBUs. From these reports, the transplant center selects a CBU(s) for further testing, which includes at a minimum confirmation of the CBUs Human Leukocyte Antigen (HLA) typing data. Upon final selection of the desired CBU for transplantation, arrangements are made for timely shipment of the unit to the transplant center. Following transplantation, recipient outcome data are submitted by the transplant center for addition to the study database.

Enrollment

3,621 patients

Sex

Female

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Pregnancy

Exclusion criteria

Trial design

3,621 participants in 1 patient group

single arm
Experimental group
Description:
HPC, Cord Blood
Treatment:
Biological: HPC, Cord Blood

Trial contacts and locations

19

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Data sourced from clinicaltrials.gov

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