Cereal-based Products Fortified With Legumes and Effects on Glycemic Control and Appetite Regulation

Harokopio University

Status: Completed

Conditions: Appetite

Treatments: Other: Reference food; Other: Cereal-legume product 1; Other: Cereal product; Other: Cereal-legume product 2

Study type: Interventional

Funder types: Other

Identifiers

NCT03974165

923.20-3-2019

Details and patient eligibility

About

Legumes are rich source of proteins and dietary fibers which are associated with satiety and amelioration of postprandial glycemic response. The purpose of the study is to examine the effects of cereal-based products fortified with legumes on appetite regulation and body weight management.

Full description

Postprandial glycemic response as well as response of hormones related to appetite regulation after consumption of cereal-based products fortified with legumes will be evaluated. Apparently healthy subjects with normal body weight and overweight subjects will participate in the study (two protocols). Certain effects on metabolites related to the composition of the different products will be examined. The results of the study will help in the design of a long-term clinical trial regarding the effects of the functional products on body weight management in overweight subjects.

Enrollment: 15 patients

Sex: All

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• normal exercise and dietary habits
• weight stable for at least 3 months before enrollment

Exclusion criteria

• pregnancy
• diabetes
• chronic medical illness
• use of nutritional supplements
• regular intense exercise
• alcohol consumption >2 drinks per day

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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15 participants in 4 patient groups

Cereal-legume product 1

Experimental group

Description:

Treatment with cereal-legume product-1

Treatment:

Other: Cereal-legume product 1

Cereal-legume product 2

Experimental group

Description:

Treatment with cereal-legume product-2

Treatment:

Other: Cereal-legume product 2

Cereal product

Experimental group

Description:

Treatment with cereal product

Treatment:

Other: Cereal product

Reference food

Active Comparator group

Description:

Treatment with reference food

Treatment:

Other: Reference food