Cereals and Intestinal Function

University of Vienna

Status: Completed

Conditions: Endotoxemia; Diet, Healthy

Treatments: Other: Dietary intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT04019457

UVienna19

Details and patient eligibility

About

The aim of the present study is to determine the effect of dietary fiber on intestinal function in healthy subjects.

Full description

In the intervention study normal weight participants will receive defined amounts of different cereal flakes for several days. Before and after intervention parameters of intestinal function will be assessed.

Enrollment: 17 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI <25 kg/m2
• daily alcohol consumption <20g (men) or <10g (women)

Exclusion criteria

• food allergies or intolerances
• instable body weight
• BMI <18,5 kg/m2 or >25 kg/m2
• bariatric surgery within the last 5 years
• intake of antibiotics within the last month or during the study
• daily alcohol consumption >20g (men) or >10g (women)
• pregnancy and/or lactation period
• viral or bacterial infection during the last three weeks
• increased inflammatory markers of unknown reason
• chronic or acute disease of gastrointestinal tract

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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17 participants in 2 patient groups

Dietary fiber 1

Experimental group

Description:

Participants receive cereal flakes 1 to include it in their normal diet.

Treatment:

Other: Dietary intervention

Dietary fiber 2

Experimental group

Description:

Participants receive cereal flakes 2 to include it in their normal diet.

Treatment:

Other: Dietary intervention