Cerebellar Loops and Attention Deficit Hyperactivity Disorder (ADHD) (TDA/H)

University Hospital of Bordeaux

Status: Terminated

Conditions: Attention Deficit Disorder With Hyperactivity

Treatments: Other: Imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT00684931

CHUBX 2007/21

Details and patient eligibility

About

The aim of this study is to investigate the integrity of connectivity between the neocortex and the cerebellum in the Attention Deficit Hyperactivity Disorder (ADHD). Fibers integrity will be measured using magnetic Resonance Imaging Techniques.

Full description

ADHD is a neurodevelopmental trouble characterized by attentional deficits, impulsivity and motor hyperactivity. Morphological neuroimaging studies in ADHD children have revealed cerebellar abnormalities, however data in adults regarding cerebellum alterations are scarce. In this study we will analyse the conectivity of the cerebellum of adults ADHD patients. We will use diffusion tensor imaging (DTI) technique, and morphological data will be compared with the neuropsychological status.

Enrollment: 19 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Patient with ADHD :

• Diagnosis of ADHD
• 18 - 35 years old

Healthy volunteer :

• 18 - 35 years old
• no ADHD diagnosed

Exclusion criteria

• Associated neurological or psychiatric pathologies
• Pregnant woman
• MRI counter indication

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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19 participants in 2 patient groups

1

Experimental group

Description:

patients with Attention Deficit Disorder with or without Hyperactivity

Treatment:

Other: Imaging

2

Sham Comparator group

Description:

healthy volunteer without Attention Deficit Hyperactivity Disorder

Treatment:

Other: Imaging