Cerebral and Peripheral Electrical Stimulation on Isometric Quadriceps Strength

Universidade Federal do Piauí

Status and phase: Completed; Phase 3; Phase 2

Conditions: Healthy Volunteers

Treatments: Device: Peripheral stimulation; Device: Cerebral stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT03870139

tDCS and knee strength

Details and patient eligibility

About

Quadriceps muscle strength is a key goal to be achieved in rehabilitation protocols for a variety of musculoskeletal conditions. Both cerebral and peripheral electrical stimulations can modulate motor brain areas involved in motor functions and has the potential to optimize muscle capacity. However, their effects on quadriceps function are lacking.

This study aims to investigate the effects of transcranial direct current stimulation (tDCS) and peripheral electrical stimulation (PES) on quadriceps strength in healthy subjects.

Enrollment: 20 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy subjects with no complaints of pain, discomfort in the musculoskeletal system.

Exclusion criteria

• Musculoskeletal or neurological disorder
• Under medication

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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20 participants in 4 patient groups

Cerebral stimulation

Active Comparator group

Description:

Active transcranial direct current stimulation tDCS: 20 minutes, 2mA, primary motor cortex anode (contralateral to the dominant lower limb) and supraorbital cathode (ipsilateral to the dominant lower limb).

Treatment:

Device: Cerebral stimulation

Combined stimulation 1

Experimental group

Description:

Active peripheral electrical stimulation (PES_sensorial) combined with active transcranial direct current stimulation tDCS: 20 minutes, 2mA, primary motor cortex anode (contralateral to the lesion) and supraorbital cathode (ipsilateral to the lesion). PES_sensorial: 20 minutes, 10Hz (frequency), 100µs (pulse duration), intensity at sensorial level.

Treatment:

Device: Cerebral stimulation

Device: Peripheral stimulation

Peripheral stimulation

Active Comparator group

Description:

Active peripheral electrical stimulation (PES_motor). PES: 15 minutes, 30Hz (frequency), 100µs (pulse duration), intensity at motor level.

Treatment:

Device: Peripheral stimulation

Combined stimulation 2

Experimental group

Description:

Active sensorial peripheral electrical stimulation (PES_sensorial) combined with active motor peripheral electrical stimulation (PES_motor) PES_sensorial: 20 minutes, 10Hz (frequency), 100µs (pulse duration), intensity at sensorial level PES_motor: 15 minutes, 30Hz (frequency), 100µs (pulse duration), intensity at motor level.

Treatment:

Device: Cerebral stimulation

Device: Peripheral stimulation