Cerebral Dynamic Perfusion Study With Spectral CT in Patients Suspected of Stroke (AVC_AIGUS)

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Status: Completed

Conditions: Stroke, Acute

Treatments: Radiation: spectral CT

Study type: Interventional

Funder types: Other

Identifiers

NCT03948425

2017/12AVR/209 (Other Identifier)

AVC AIGUS

Details and patient eligibility

About

• Generate a dynamic mapping of the distribution of iodine within the cerebral parenchyma in the patient suspected of acute ischemic disorder with the CT spectral scanner.
• Correlate the anomalies of iodine mapping to the other parameters acquired during the classic dynamic infusion phase to define the ischemic area (MTT higher and rCBV normal) versus infarcted zone (MTT higher and rCBV decreased)

Enrollment: 28 patients

Sex: All

Ages: 50 to 95 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical suspicion of hyperacute stroke (6 hours after onset of symptoms)
• Age between 50 and 95 years
• Weight: between 65 and 95 kg

Exclusion criteria

• Documented or suspected allergy to IV iodinated contrast media
• Renal impairment with creatinine clearance <60 ml / min
• Hemorrhagic lesions or vascular abnormalities demonstrated on CT before contrast injection

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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28 participants in 1 patient group

Stroke

Experimental group

Description:

Clinical suspicion of hyperacute stroke (6 hours after onset of symptoms):Intervention 'spectral CT'

Treatment:

Radiation: spectral CT