Cerebral Excitability and Cognitive Performance

Tufts University

Status: Unknown

Conditions: Cognitive Change

Treatments: Other: Stimulation via Soterix Medical or Neuroelectrics noninvasive brain stimulation systems

Study type: Interventional

Funder types: Other

Identifiers

NCT03807934

1303018

Details and patient eligibility

About

This study investigates the perceptual and cognitive influences of low-intensity electrical brain stimulation (transcranial direct current stimulation; tDCS), versus control (sham) conditions.

Enrollment: 1,500 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Between ages of 18-65.

Exclusion criteria

• History of adverse reaction to tDCS (trans-cranial direct current stimulation).
• History of seizure activity.
• History of head injury (including neurosurgery).
• History of illness causing brain injury.
• History of other brain-related condition (such as traumatic brain injury).
• History of diagnosis with a neurological or psychiatric disorder.
• History of metal in head (outside of mouth), such as shrapnel, surgical clips, or fragments from welding or metalwork.
• History of sensitive scalp.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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1,500 participants in 2 patient groups

Active High-Definition Stimulation

Experimental group

Description:

Active high-definition stimulation of targeted brain regions involved in perception and cognition.

Treatment:

Other: Stimulation via Soterix Medical or Neuroelectrics noninvasive brain stimulation systems

Sham High-Definition Stimulation

Sham Comparator group

Description:

Sham high-definition stimulation of targeted brain regions involved in perception and cognition.

Treatment:

Other: Stimulation via Soterix Medical or Neuroelectrics noninvasive brain stimulation systems