Cerebral Oximetry With Near-infrared Spectroscopy and Negative Postoperative Behavioral Changes in Pediatric Surgery

Hospital Clínico Universitario de Valladolid

Status: Completed

Conditions: Cognitive Dysfunction

Treatments: Other: monitoring cerebral oxygen saturation

Study type: Observational

Funder types: Other

Identifiers

NCT02773186

NPOBC

Details and patient eligibility

About

The main objective of the present study was to evaluate whether cerebral oxygen saturation is associated with an increase of NPOBC in pediatric patients undergoing major surgery.

Full description

This prospective and observational study involved consecutive patients aged between 2 and 12 years undergoing a major surgery using general anesthesia. Cerebral oxygen saturation, non-invasive arterial pressure, pulse oximetry, and heart rate were recorded at the following stages of the surgical intervention: baseline, induction, intubation, surgical incision, end of surgery, and extubation. Preoperative anxiety was evaluated by using the modified Yale Preoperative Anxiety Scale, and NPOBC was determined by using the Post-Hospital Behaviour Questionnaire on 7th and 28th postoperative days. A logistic regression was created to identify factors associated with the development of NPOBC

Enrollment: 198 patients

Sex: All

Ages: 2 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged between 2 and 12 years undergoing major surgery using general anesthesia.

Exclusion criteria

• Children aged below 2 or over 12.
• Neuropsychiatric disorder, or undergoing an emergency surgery.