Cerebral Oxygenation and Neurological Functioning After Cardiac Surgery (CONFUSE)

Dr. Gordon Boyd

Status: Enrolling

Conditions: Coronary Artery Disease; Delirium; Cognitive Impairment

Study type: Observational

Funder types: Other

Identifiers

NCT04081649

DMED-1672-14

Details and patient eligibility

About

The overall goal of this research program is to determine quantitative predictors of quantitative long-term neurological functioning following different cardiac surgery procedures. The investigators aim to generate a timeline of neurological function that includes pre-existing performance, post-operative delirium, and neurological outcome. Furthermore, the investigators will test the hypothesis that intraoperative regional cerebral oxygenation (rSO2) desaturations, as measured by near-infrared spectroscopy (NIRS) are associated with poor neurological functioning following cardiac surgery, as measured by a robotic device called the KINARM.

Enrollment: 95 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients undergoing coronary artery bypass surgery +/- valvular surgery

Exclusion criteria

• pre-existing cognitive impairment or neurodegenerative condition
• any reason that participant cannot participate in follow up (lives too far away, limb amputation, speaks language other than english)

Trial design

95 participants in 1 patient group

Cardiac surgery

Description:

Patients undergoing non-emergent cardiac surgery for coronary bypass graft and/or valvular replacement