Cerebral Oxymetry and Neurological Outcome in Therapeutic Hypothermia

Tepecik Training and Research Hospital

Status

Completed

Conditions

Cardiac Arrest

Post-Cardiorespiratory Arrest Coma

Hypoxic-Ischemic Encephalopathy

Treatments

Device: Near-infrared spectroscopy (NIRS) (INVOS®, Covidien)

Study type

Observational

Funder types

Other

Identifiers

NCT03024021

29/3

Details and patient eligibility

About

This study is designed to assess the effect of cerebral oxygen saturation as an early predictor of neurological outcomes in patients undergoing therapeutic hypothermia after cardiac arrest

Full description

Our study is planned as a prospective observational study. Patients undergoing therapeutic hypothermia in our intensive care unit after cardiac arrest will be enrolled. Each patient's cerebral oxygenation will be monitored with near-infrared spectroscopy (NIRS) in every 6 hours during our 24 hour lasting hypothermia period. Afterwards, patients will be monitorised in every 6 hours during the first day of hypothermia and than the mean values of daily cerebral oxygen values will be noted in the third, fourth and fifth days of nomothermia. Regional oxygen saturation (rSO2) will be noted from left and right probes. Full Outline of Unresponsiveness (FOUR) Score, Glasgow Coma Score (GCS) and cerebral performance category scale (CPC) will be noted at the beginning of therapeutic hypothermia and each day during normothermia, day 21 and the day of discharge from ICU.

Enrollment

100 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria