Cerebromicrovascular Effects of Time-Restricted Eating in Older Adults

University of Oklahoma (OU)

Status: Completed

Conditions: Time Restricted Eating

Treatments: Other: Time restricted eating

Study type: Interventional

Funder types: Other

Identifiers

NCT05488652

14856

Details and patient eligibility

About

The central hypothesis of this study is that closer adherence to time restricted eating (TRE) will improve endothelial function, neurovascular (NVC) responses, resulting in improved cognitive performance, potentially through activation of SIRT1-dependent vasoprotective pathways.

Full description

This hypothesis will be tested by assessing the effect of TRE (not more than 10hr eating window each day for 6 months) in healthy adults (≥21 years of age). The group of subjects enrolled into TRE arm will be compared to control group. All participants will be randomized into either arm of the study.

Enrollment: 10 patients

Sex: All

Ages: 21+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

-Healthy adults ≥21 years of age

Exclusion criteria

-Inability to read or write in English

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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10 participants in 2 patient groups

Control

No Intervention group

Description:

no intervention

Time restricted eating

Experimental group

Description:

not more than 10 hrs. eating window daily goal for 6 months

Treatment:

Other: Time restricted eating