Certain Maternal Antibodies in Relation to Doppler in Hypertension With Pregnancy

Cairo University (CU)

Status: Unknown

Conditions: Pre-Eclampsia

Treatments: Diagnostic Test: Doppler; Diagnostic Test: serum antibodies

Study type: Observational

Funder types: Other

Identifiers

NCT03214393

3650

Details and patient eligibility

About

Relation of certain maternal serum antibodies to Doppler changes will be studied in cases suffering from hypertension with pregnancy.

Full description

Assessment will be done for maternal serum anti-beta 2 glycoprotein 1 antibodies and anticardiolipin antibodies in cases of preeclampsia after 32 weeks of pregnancy. In addition, fetal Doppler changes will be assessed.

Enrollment: 100 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pregnant women 32 weeks or more gestational age
• Pre-eclampsia
• Singleton pregnancy

Exclusion criteria

• Intrauterine fetal death
• Fetus with apparent congenital anomalies
• Pregnant females with other medical disorders
• History of essential hypertension.
• History of antepartum hemorrhage.
• History of rupture of membranes.

Trial design

100 participants in 1 patient group

Pre-Eclampsia

Description:

pregnant women with Pre-Eclampsia will be assessed by serum antibodies and Doppler

Treatment:

Diagnostic Test: Doppler

Diagnostic Test: serum antibodies