Cervical Cancer Screening in HIV Positive and Negative Women in Cambodia

Sihanouk Hospital Center of HOPE

Status: Completed

Conditions: Cervical Neoplasia; Cervical Cancer

Treatments: Procedure: cryotherapy, further biopsy, LEEP, surgery as indicated

Study type: Observational

Funder types: Other

Identifiers

NCT02253719

SHCH-Cervical Screening-VIA

Details and patient eligibility

About

The prevalence of cervical neoplasia in Cambodia is not known. There are no screening programs in place. The investigators plan on introducing a screening program based on WHO criteria and utilizing visualization with acetic acid. Patients who are positive will be offered same-day cryotherapy if indicated or will be referred for biopsy, LEEP and hysterectomy as indicated. The planned patient pool for this study is 1000 women, half of whom will be HIV positive (and thus have a presumed higher incidence of cervical neoplasia).

Enrollment: 1,000 patients

Sex: Female

Ages: 30 to 49 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• female, age 30-49, able to give informed consent

Exclusion criteria

• pregnancy, gross cervical mass, prior cervical cancer, unable to give informed consent, prior complete hysterectomy, allergic to acetic acid

Trial design

1,000 participants in 2 patient groups

HIV positive women

Description:

500 HIV women will be recruited from the hospital's current patient base as well as the community

Treatment:

Procedure: cryotherapy, further biopsy, LEEP, surgery as indicated

HIV negative women

Description:

500 HIV women will be recruited from the hospital's current patient base as well as the community

Treatment:

Procedure: cryotherapy, further biopsy, LEEP, surgery as indicated