CGM Use in Islet Transplant Recipients

University of Virginia

Status

Completed

Conditions

Islet Transplantation

Type1 Diabetes Mellitus

Treatments

Other: Continuous Glucose Monitor (CGM)

Study type

Interventional

Funder types

Other

Industry

Identifiers

NCT03427931

20294

Details and patient eligibility

About

A study assessing glucose variability in subjects with Type 1 Diabetes who have had islet transplant.

Full description

Subjects who have an Islet Transplantation may have several outcomes including time when insulin is not required followed in some cases by additional insulin for glucose control as patients get further away from transplantation. It is unclear what role automated insulin delivery systems will have in addressing glucose variability in this group of patients who may have some amount of islet function. As a precursor to understanding ways in which automated insulin delivery systems may need to be adapted, we propose to gather data on glucose variability and insulin regimens in individuals who have undergone an islet transplantation.

Enrollment

7 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Type 1 Diabetes Mellitus
Recipient of Islet Transplantation
Age 18 or older
Females, not currently know to be pregnant
Demonstration of proper mental status and cognition for the study
Understanding and willingness to follow the protocol and informed consent form
Access to the internet and willingness to upload data during the study, including use of personal laptop

Exclusion criteria

Pregnancy and intent to become pregnant during trial
Use of acetaminophen (such as Tylenol)
Current enrollment in another intervention clinical trial that affects glucose variability