Change in Brain Metabolism and Cognitive Function by Aripiprazole

Seoul National University

Status: Completed

Conditions: Dopamine Receptor Occupancy; Brain Metabolism; Cognition; Antipsychotics

Treatments: Drug: Aripiprazole

Study type: Interventional

Funder types: Other

Identifiers

NCT01562808

A070001 (Other Grant/Funding Number)

Details and patient eligibility

About

Dopamine receptor occupancy and brain metabolism were measured using positron emission tomography after the administration of aripiprazole. Working memory performance was also measured using N-back task.

The investigators explored the relationship between changes in brain metabolism and working memory performance.

Enrollment: 15 patients

Sex: Male

Ages: 19 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy volunteers
• right-handed

Exclusion criteria

• any significant abnormality on routine lab
• any psychiatric disease

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind