Change in Tongue Strength and Fatigue After Upper Airway Stimulation Therapy

Technical University of Munich

Status: Completed

Conditions: Obstructive Sleep Apnea of Adult

Study type: Observational

Funder types: Other

Identifiers

NCT03980158

425/17S

Details and patient eligibility

About

Upper airway stimulation (UAS) is an effective surgical alternative for patients with obstructive sleep apnea (OSA) who fail continuous positive airway pressure (CPAP) therapy. This stimulation could lead to alterations in tongue strength and fatigability which could alter treatment outcome. The aim of the study is to investigate if UAS alters tongue strength and fatigability.

Enrollment: 103 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18 years old or older
• upper airway stimulation group: Upper airway stimulation system implanted at least 4 weeks ago
• OSA group: OSA confirmed by 18-channel inpatient overnight polysomnography (PSG)
• test group: No medical history for OSA and Epworth Sleepiness Scale (ESS) below 11

Exclusion criteria

• history of a neuromuscular disorder
• previous tongue surgery

Trial design

103 participants in 3 patient groups

Upper airway stimulation group

OSA group with conservative / no treatment

Test group without OSA