Changes in Cerebral Oxygenation Studies During Laparoscopy Procedure

Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences

Status: Completed

Conditions: Cerebral Perfusion and Oxygenation; Laparoscopy; Increase in Intra-abdominal Pressure; Increase in Intracranial Pressure (ICP)

Treatments: Procedure: Laparoscopy

Study type: Observational

Funder types: Other

Identifiers

NCT03640741

IAP_UMLub_GBox

Details and patient eligibility

About

The motivation results from the fact, that an intra-abdominal pressure is correlated with cerebral perfusion, in a mechanism of reducing venous outflow. Moreover, elevated intra-abdominal pressure leads to increase in intracranial pressure and decrease of cerebral perfusion pressure.

The main aim of the study was to investigate an influence of increase in intra-abdominal pressure on cerebral oxygenation measured with the use of non-invasive optical technique.

Full description

The investigators applied time resolved near infrared spectroscopy device in order to estimate changes in hemoglobin concentration in a brain during gynecological procedure that involves laparoscopy. The optodes were positioned on a forehead on left and right hemisphere.

The measurements were carried out during whole medical procedure, including anesthesia, start and stop of insufflation of abdominal cavity with carbon dioxide (CO2), surgical procedure, release of CO2 and waking up a patient. In those studies the special emphasis was put on a period of insufflation of abdominal cavity with CO2.

Enrollment: 17 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• laparoscopic procedure

Exclusion criteria

• no consent

Trial design

17 participants in 1 patient group

Laparoscopy

Description:

The group consists of patients who undergoes laparoscopy procedure during which changes in cerebral oxygenation are estimated.

Treatment:

Procedure: Laparoscopy