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Changes in Cerebrovascular Reactivity During Cognitive Activation After Cardiopulmonary Bypass: Relation With Intraoperative Embolic Load and Postoperative Neuropsychological Dysfunctions

U

University Ghent

Status

Completed

Conditions

CABG-Patients

Treatments

Procedure: Determination of neuropsychological status

Study type

Interventional

Funder types

Other

Identifiers

NCT00394108
1997/098

Details and patient eligibility

About

The study aims to evaluate neuropsychological disorders in CABG patients. Measurements are performed 1 day before, 6 days, 6 months and 3-5 years after the surgery. The relation with cerebrovascular reactivity and embolic load (measured by transcranial Doppler Ultrasonography) is evaluated. Two surgery techniques (on- and off-pump CABG) are compared.

Enrollment

66 patients

Sex

All

Ages

18 to 69 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • CABG-patients (not urgent)
  • < 70 years old
  • Righthanded

Exclusion criteria

  • Neurological or psychiatric disease
  • Psychoactive medication
  • Valve operation

Trial design

Primary purpose

Diagnostic

Allocation

Randomized

Interventional model

Single Group Assignment

Masking

None (Open label)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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