Changes in Cerebrovascular Reactivity During Cognitive Activation After Cardiopulmonary Bypass: Relation With Intraoperative Embolic Load and Postoperative Neuropsychological Dysfunctions

University Ghent

Status: Completed

Conditions: CABG-Patients

Treatments: Procedure: Determination of neuropsychological status

Study type: Interventional

Funder types: Other

Identifiers

NCT00394108

1997/098

Details and patient eligibility

About

The study aims to evaluate neuropsychological disorders in CABG patients. Measurements are performed 1 day before, 6 days, 6 months and 3-5 years after the surgery. The relation with cerebrovascular reactivity and embolic load (measured by transcranial Doppler Ultrasonography) is evaluated. Two surgery techniques (on- and off-pump CABG) are compared.

Enrollment: 66 patients

Sex: All

Ages: 18 to 69 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• CABG-patients (not urgent)
• < 70 years old
• Righthanded

Exclusion criteria

• Neurological or psychiatric disease
• Psychoactive medication
• Valve operation

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)