Changes in Echogenicity and Muscle Stiffness in Elastography After Botulinum Toxin Injection a Spastic Muscle

Centre Hospitalier Universitaire de Saint Etienne

Status: Terminated

Conditions: Stroke

Treatments: Device: ultrasound echogenicity; Device: elastography

Study type: Interventional

Funder types: Other

Identifiers

NCT02550509

1301141

Details and patient eligibility

About

Muscle alterations and modifications passive biomechanical properties that occur on a spastic muscle contribute to functional disorders involved in spasticity. Botulinum toxin (TB) A is the reference treatment of the focused spasticity, and muscle source structural and biomechanical changes, very little studied in humans, especially since it is not one possibility of easily and reliably paraclinical assessment injections consequences.

Enrollment: 6 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• A first stroke older than nine months (acute phase and subacute stroke).
• Hemiplegia cerebral vascular following this stroke.
• Hemiplegia with an overall motor deficit plegic lower limb muscle testing level less than or equal to 3 and associating a localized spasticity lower plegic member, on the plantar flexors, assessed by the upper Ashworth Scale or equal to 1 with an injection of botulinum toxin indication of the sural triceps.
• written consent.

Exclusion criteria

• Old stroke with motor impairment of the lower limb in the chronic stage.
• Concomitant muscle disease (eg myopathy, myositis ...).
• Patients who already received a botulinum toxin injection into the gastrocnemius muscles.
• Subjects with defibrillator

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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6 participants in 1 patient group

patients with hemiplegia after stroke

Experimental group

Description:

ultrasound echogenicity paraclinical assessment and elastography to patients with hemiplegia following stroke with an indication of injection of botulinum toxin into the triceps sural

Treatment:

Device: ultrasound echogenicity

Device: elastography