Changes in Habitual Physical Activity and Inactivity (START)

University of Massachusetts, Amherst

Status: Completed

Conditions: Habitual Physical Activity; Sedentary Time

Treatments: Behavioral: exercsie training plus sedentary time reduction; Behavioral: sedentary time reduction; Behavioral: exercise training

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT01580930

RC1HL099557 (U.S. NIH Grant/Contract)

Kozey-Keadle

Details and patient eligibility

About

The purpose of this study is to determine if individuals involved in exercise training change habitual activity and inactivity behavior outside of exercise training. Eligible participants were randomly assigned to one of four groups: control, exercise training, sedentary time reduction, or exercise training plus sedentary time reduction. It was hypothesized that participants in the exercise training group will compensate for exercise training by reducing free-living physical activity behavior and increasing sedentary time. Participant free-living behavior was monitored for one week at baseline, 3, 6, 9 and 12 weeks using an activPAL wearable monitor.

Enrollment: 57 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Eligible participants were those at increased risk of cardiovascular disease, based on meeting two of the following three criteria:

1. Pre-hypertensive: resting blood pressure between 125-160 mm Hg systolic and/or 85-100 mm Hg diastolic,
2. overweight/obese: body mass index (BMI) between 25 and 45 kg∙m-2,
3. high central adiposity: as defined by elevated natural waist circumference (> 102 cm [males] > 88cm [females]), a surrogate measure of visceral fat
4. low aerobic fitness (VO2 peak ≤ 50th percentile of age and sex specific norms)
5. exercising less than three days per week for less than 20 minutes per session for the preceding six months

Exclusion criteria

• major orthopedic limitations,
• wheelchair use or musculoskeletal problems that affected mobility,
• life-threatening illness (e.g., terminal cancer),
• chronic diseases (e.g., diagnosed heart disease, diabetes, emphysema) or
• any condition for which a physician did not recommend exercise. Participants were excluded if they had gastric bypass or lap-band surgery within the last year, were taking medication for type II diabetes (e.g. metformin) or beta-blocker medication for high blood pressure.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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57 participants in 4 patient groups

Control group

No Intervention group

Description:

Group had outcome measures collected and were instructed to not change activity and sedentary time behavior

Exercise

Experimental group

Description:

Participants performed 5 days per week, 40 min per session of exercise training under direct supervision of personal trainer.

Treatment:

Behavioral: exercise training

Sedentary time reduction

Experimental group

Description:

participants were give strategies to reduce sedentary time

Treatment:

Behavioral: sedentary time reduction

exercise plus sedentary time reduction

Experimental group

Description:

Participants completed exercise training (5 days per week, 40 min per session) plus were given sedentary time reduction intervention

Treatment:

Behavioral: exercsie training plus sedentary time reduction