Changes in High Sensitive C Reactive Protien With Different Treatment Modalities in Acute Pancreatitis

Assiut University

Status: Unknown

Conditions: Pancreatitis, Acute

Treatments: Diagnostic Test: High sesitive C reactive protien

Study type: Observational

Funder types: Other

Identifiers

NCT03740685

CHCPWDTM

Details and patient eligibility

About

changes in high sensitive C reactive protien with different treatment modalities in acute pancreatitis

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age>=18 years

• Diagnosis of acute pancreatitis confirmed by at least 2 of the following:

  1. Typical epigastric abdominal pain
  2. Elevation amylase/lipase >3 times upper limit normal and/or
  3. Confirmatory findings on cross-sectional imaging
  4. Enrollment within 8 hours of presentation

Exclusion criteria

• Class II or greater NYHA heart failure
• Oxygen dependent COPD
• Chronic kidney disease>stage 2
• Existing necrosis on abdominal CT
• Organ dysfunction prior to enrollment
• Sepsis
• Acute respiratory distress syndrome
• Malignancy not in remission for at least 5 years
• Active drug use
• Known allergy to dexamethasone
• Altered mental status
• Insulin-requiring diabetes
• Abdominal surgery within 60days

Trial design

80 participants in 1 patient group

Patients with acute pancreatitis

Description:

All patients will recive different lines of treatment {saline,antibiotics,dexamethasone}

Treatment:

Diagnostic Test: High sesitive C reactive protien