Changes in Muscle Morphology Resulting From Anterior Cruciate Ligament Reconstruction

Panam Clinic

Status: Completed

Conditions: Isolated Anterior Cruciate Ligament Rupture

Treatments: Other: Autograft STG harvest from ACL-deficient leg; Other: Autograft harvest contralateral to ACL-deficient leg

Study type: Interventional

Funder types: Other

Identifiers

NCT01537588

April 2009

Details and patient eligibility

About

The aim of this study is to gain new knowledge on the impact of hamstring tendon harvest and apply that knowledge to the treatment and management of patients who undergo anterior cruciate ligament (ACL) reconstruction. There are three main components of this study:

1. How do muscle shape, size, strength, and ability to function change following hamstring grafting for ACL reconstruction;
2. How does physical activity change following ACL reconstruction;
3. Is there a difference in outcome if graft harvest is done from the injured versus uninjured limbs

Enrollment: 30 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• between 18 and 50 years old; isolated ACL rupture confirmed on MRI

Exclusion criteria

• other physical or mental health issues that affect ability to complete rehabilitation and/or study follow-ups

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

30 participants in 3 patient groups

Standard

Active Comparator group

Description:

ACL reconstruction with autograft harvest of STG from ACL-deficient leg

Treatment:

Other: Autograft STG harvest from ACL-deficient leg

Autograft harvest of STG from ACL-deficient leg

Experimental group

Description:

Autograft harvest of STG from leg contralateral to ACL-deficient leg

Treatment:

Other: Autograft harvest contralateral to ACL-deficient leg

Normal matched

No Intervention group