Changes in Regional and Global Cardiac Contractility After Stimulation in Scar Zone with the NOGA System (SCARPACE)

Toulouse University Hospital

Status: Enrolling

Conditions: Myocardial Infarction

Treatments: Device: NOGA TM probe

Study type: Interventional

Funder types: Other

Identifiers

NCT04757168

RC31/19/0513

Details and patient eligibility

About

Despite a decrease in voltage amplitude in post-infarction scar areas, greater voltage amplitudes are sometimes observed at the time of local extrasystoles mechanically induced by catheters.

However, no study has investigated whether these electrical changes are associated with mechanical changes in local contractility.

However, the voltage is closely correlated to the local contractile function as evidenced by the use of the NOGA system.

Enrollment: 12 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who should undergo ventricular tachycardia (VT) ablation after a myocardial infarction according to current recommendations, namely: patients with ischemic heart disease (ICD) and with episodes of sustained ventricular tachycardia responsible for internal electric shocks by the implantable automatic defibrillator (ICD) (grade IB recommendation)

OR

• patients with an MIC and an ICD, presenting a first episode of sustained ventricular tachycardia (grade IIa, B recommendation)
• Affiliated with a social protection scheme
• Having signed an informed consent

Exclusion criteria

• Contraindication or non-indication for ventricular tachycardia ablation
• Women who are pregnant or of childbearing age and without contraception, breastfeeding women
• Patients without ischemic heart disease
• Patients under guardianship, curatorship or legal protection.

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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12 participants in 1 patient group

NOGA TM probe

Experimental group

Treatment:

Device: NOGA TM probe