Changes in Tactile Perception in People With Segmental Exclusion Syndrome

Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est

Status: Completed

Conditions: Upper Limb Exclusion Syndrom

Study type: Observational

Funder types: Other

Identifiers

NCT05650398

IRR-CLP-2022-9

Details and patient eligibility

About

Segmental exclusion syndrome is characterised by the non-use or under-use of a limb segment, most oftenly reported in the distal part, following an injury, without affecting the central nervous system. This syndrome has an important negative impact on the daily life of affected subjects; however, it remains poorly studied, particularly in terms of pathophysiology, and its management is still not specific. Currently, the main pathophysiological hypothesis is an alteration of the afferences related to a dysfunction of the sensorimotor loop. An hypothesis is that this dysfunction could concern the level of tactile perception and that the damage to the distal light touch receptors could play a role in the pathophysiology. The protocol is based on the performance of tests that explore different aspects of light touch: passive, active, dynamic and static sensitivity.

Enrollment: 34 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• No history of upper limb involvement
• Confirmed diagnosis of segmental exclusion > 3 months after injury (2 items assigned to 400 points)
• Able to understand simple orders

Exclusion criteria

• Central neurological involvement after the initial or pre-existing injury
• Truncal nerve damage
• Presence of psychiatric pathology
• Communication and/or comprehension disorders
• Presence of other pathology that may lead to sensory disorders (complicated diabetes, ductal syndrome, ...)

Trial design

34 participants in 2 patient groups

Patients with exclusion

Description:

Evaluation of the tactile sensitivity of the excluded finger using different tests: Static and dynamic two-points discrimination tests, the Semmes-Weinstein monofilament test, grating orientation task and the bar test inspired by the study of Louw et al. Realization of the same tests on the controllateral healthy finger.

Control

Description:

Evaluation of the tactile sensitivity of the finger using different tests: Static and dynamic two-points discrimination tests, the Semmes-Weinstein monofilament test, grating orientation task and the bar test inspired by the study of Louw et al. Realization of the same tests on the controllateral finger.