Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning in Patients With Type 1 Diabetes

University of Aarhus

Status: Completed

Conditions: Diabetes Mellitus, Type 1; Diabetes Complications; Ischemia; Retinal Ischemia

Treatments: Other: Remote Ischemic Conditioning

Study type: Interventional

Funder types: Other

Identifiers

NCT03906383

RIK_RVA Diabetes

Details and patient eligibility

About

Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury. It remains unknown whether this can be used in retinal ischemic diseases. The purpose of the present study is to examine if the autoregulation of retinal vessel diameters in diabetic patients change after remote ischemic conditioning and if the observations are different from what have been observed in normal persons.

Enrollment: 21 patients

Sex: All

Ages: 20 to 31 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diabetes type 1
• Diabetic retinopathy

Exclusion criteria

• Previous treatment for diabetic retinopathy
• Other ocular and systemic diseases requiring treatment
• Pregnancy or lactation

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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21 participants in 1 patient group

Remote Ischemic Conditioning

Experimental group

Treatment:

Other: Remote Ischemic Conditioning