Changes in the Permeability of the Blood Brain Barrier and Intestinal Barrier in Humans During Conditions of Stress and Immune Activation: in Vivo Studies

National University Health System (NUHS)

Status: Completed

Conditions: Combat Training Stress

Study type: Observational

Funder types: Other

Identifiers

NCT01417416

C/08/236

DSOCL08210 (Other Grant/Funding Number)

Details and patient eligibility

About

The relevance of BBB and IB permeability changes as a major precipitating cause for cognitive and digestive dysfunction in the military stress setting.

Sex: Male

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Healthy male troops (aged 18-50 yrs) scheduled to be engaged in a protracted multi-day stressful field exercises.

Exclusion criteria

• Significantly systemic disease, including cardiovascular, psychiatric, neurological (including polyneuropathies) and endocrine disease including diabetes mellitus.
• No written informed consent obtained from subject.

Trial design

0 participants in 2 patient groups

with combat training stress

without combat training stress