Changes of Dendritic Cells in Acute Lung Injury

Southeast University, China

Status: Completed

Conditions: Acute Lung Injury

Study type: Observational

Funder types: Other

Identifiers

NCT02083393

SoutheastUChina2011ZDllKY04

Details and patient eligibility

About

To observe changes of circulating and tissue dendritic cells in acute lung injury,including invasive aspergillosis pneumonia

Full description

Change of circulating and tissular dendritic cells of patients with acute lung injury was still unclear, we used a flow cytometry-based assay to quantify circulating and tissular DCs and their HLA-DR surface expression at the time of diagnosis and during the first week of evolution in patients with acute lung injury, and healthy people as controls.

Enrollment: 19 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Sepsis induced acute lung injury

Exclusion criteria

• Younger than 18-year-old
• Pregnancy
• Cancer or organ transplant
• Asthma
• COPD
• Heart Failure

Trial design

19 participants in 2 patient groups

Patients with acute lung injury

Description:

Patients with sepsis induced acute lung injury

Postsurgery patients

Description:

Postsurgery patients without acute lung injury and sepsis