Changes of Endothelial Function Before and After DSA in Patients With Diabetes

Wuhan General Hospital of Guangzhou Military Command

Status: Completed

Conditions: Diabetes

Treatments: Other: DSA assay

Study type: Observational

Funder types: Other

Identifiers

NCT01556984

wz2010007

Details and patient eligibility

About

Endothelial dysfunction is the early step of atherosclerosis. Therefore, the investigators hypothesize that digital subtraction angiography (DSA) can damage endothelial function. In this study, the investigators will select 200 diabetic patients who have a DSA for diabetic foot screening. Also, the investigators will select 100 healthy subjects as controls. The endothelial function will be determined by high resolution ultrasound before and after DSA. The investigators will observe the changes of endothelial function after DSA assay.

Enrollment: 200 estimated patients

Sex: All

Ages: 40 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with diabetic foot
• Age 40 to 70 years old

Exclusion criteria

• Heart failure
• Renal failure
• Acute infection

Trial design

200 participants in 2 patient groups

DSA group

Treatment:

Other: DSA assay

control group