Changes of Ocular Structures After Hemodialysis in Patients With Chronic Kidney Diseases

Hanyang University

Status: Completed

Conditions: Hemolysis; Chronic Kidney Diseases

Treatments: Other: ophthalmologic exams

Study type: Observational

Funder types: Other

Identifiers

NCT03434145

2016-05-005

Details and patient eligibility

About

To evaluate the effect of hemodialysis on various ophthalmologic parameters in patients with end-stage kidney disease (ESRD).

Full description

Subjects: patients with ESRD undergoing hemodialysis at the Dialysis Center of Hanyang Guri Hospital

Ocular parameters: visual acuity, intraocular pressure, axial length, OCT Other systemic parameters: body weight, ultrafiltration volume, and systolic/diastolic blood pressure

All measurements were performed near the dialysis center. Measurements were performed on Monday (for patients who underwent dialysis sessions on Monday, Wednesday, and Friday) or Tuesday (for patients who underwent dialysis sessions on Tuesday, Thursday, and Saturday.

All parameters were measured before and after the hemodialysis.

Enrollment: 40 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. patients who are regularly dialyzed in our dialysis room to participate in the study
• 2. patients who agree with our study protocol
• 3. patients who have unstable general condition

Exclusion criteria

• 1. previous intraocular surgery, (2) baseline IOP greater than 22 mmHg, (3) presence of glaucomatous optic disc changes including excavation, thinning, or notching of the neuroretinal rim, (4) axial length greater than 26 mm, and (5) combined macular and retinal diseases such as central serous chorioretinopathy and age-related macular degeneration, except diabetic retinopathy.

Trial design

40 participants in 1 patient group

patients with chronic kidney diseases

Description:

patients with end stage retinal disease undergoing hemodialysis underwent various ophthalmologic exams before and after hemodialysis.

Treatment:

Other: ophthalmologic exams