Changes of Regional Tissue Oxygenation Saturation After Successful Femoral Nerve Block

Huazhong University of Science and Technology

Status: Completed

Conditions: Anesthesia, Local

Treatments: Device: tissue oxygenation saturation

Study type: Observational

Funder types: Other

Identifiers

NCT03753594

XH20181118

Details and patient eligibility

About

Regional tissue oxygenation saturation has been shown to increase in innervated regions after sympathetic block. The aim of this prospective observational study was to evaluate the changes of regional tissue oxygenation saturation by near-infrared spectroscopy after successful femoral nerve block with ropivacaine and determine whether the changes of regional tissue oxygenation saturation can be affected by the concentration of ropivacaine.

Full description

Successful peripheral nerve blocks induce sympathetic blockade, which increases local blood flow by vasodilation. The relationship between successful femoral nerve block and the variation of regional tissue oxygenation saturation was unclear.

Enrollment: 100 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Informed consent
• American Society of Anesthesiologists physical statusⅠ-Ⅱ
• Undergo elective elective knee arthroscopy with peripheral nerve block

Exclusion criteria

• Refusal to participate in the study
• BMI>35
• Any contraindications to peripheral nerve block such as coagulation abnormalities, •Allergy to local anaesthetics, peripheral neuropathy

Trial design

100 participants in 2 patient groups

H group

Description:

Patients scheduled for elective knee arthroscopy with peripheral nerve block will receive ultrasound-guided femoral nerve block with 0.5% ropivacaine. Regional tissue oxygenation saturation of the nerve innervation area and pinprick sensory tests at 5 min were assessed before the block and at 5-min intervals till 30 min after the block.

Treatment:

Device: tissue oxygenation saturation

L group

Description:

Patients scheduled for elective knee arthroscopy with peripheral nerve block will receive ultrasound-guided femoral nerve block with 0.25% ropivacaine. Regional tissue oxygenation saturation of the nerve innervation area and pinprick sensory tests were assessed at 5 min before the block and at 5-min intervals till 30 min after the block.

Treatment:

Device: tissue oxygenation saturation