Characterisation of Occupational Allergy to Drosophila (DROSOALLERG)

University Hospital Center (CHU)

Status: Completed

Conditions: Drosophila; Clinical Symptoms

Treatments: Other: blood test (four dry tubes 7ml) and prick tests

Study type: Interventional

Funder types: Other

Identifiers

NCT02535793

UF 9410

Details and patient eligibility

About

Allergy is a very common problem and can be a handicap in everyday life, specially when symptoms occur at work place. Some persons working with drosophila developed respiratory symptoms. Investigators tried to analyze if these manifestations could be due to a specific allergy to drosophila.

Full description

To do so, investigators invited laboratory workers who presented any symptoms in presence of drosophila to undergo skin prick tests in order to determine if a specific sensibilization to drosophila exists. Then, a blood sample is taken from these persons to research specific IgE directed against drosophila. By this way, investigators hope determine if a specific allergy to drosophila exists, its characteristics as prevalence, symptoms, populations concerned...in order to better protect laboratory workers and prevent allergy incidence.

Enrollment: 12 patients

Sex: All

Ages: 18 to 68 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• major males or females (aged <68) who work in laboratory with drosophila in Montpellier (France)
• clinical symptoms in presence of drosophila
• The subject must be affiliated to a social security scheme
• Provision of informed consent prior to any study specific procedures

Exclusion criteria

• The patient has indicated against (or incompatible drug combination) concerning the implementation of a prick test
• antihistamine cure in progress
• Inability to understand the nature and goals of the study and / or communication difficulties with the investigator
• No affiliation to a French social security recipient or not such a scheme
• Major protected by law (guardianship, curator or under judicial protection)
• deprivation of liberty by judicial or administrative decision
• Increased likelihood of non compliance to the protocol or abandonment under study
• pregnancy or breastfeeding

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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12 participants in 1 patient group

laboratory workers with symptoms in presence of drosophila

Other group

Treatment:

Other: blood test (four dry tubes 7ml) and prick tests