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Characteristics of Patients With Amyloidosis & Heart Failure Being Evaluated for a Heart Transplant

Mass General Brigham logo

Mass General Brigham

Status

Completed

Conditions

Cardiomyopathy

Study type

Observational

Funder types

Other

Identifiers

NCT00456040
2007-p-000302

Details and patient eligibility

About

The purpose of this study is to describe the characteristics of patients with amyloidosis and severe heart failure being evaluated for cardiac and stem cell transplantation.

Full description

Systemic amyloidosis is a progressive disease leading to organ failure and death. Treatment has improved survival with stem-cell transplantation. Unfortunately, patients with amyloidosis and severe heart failure are not eligible for stem-cell transplantation.

The average rate of survival for patients with amyloidosis who receive a heart transplant is decreased.

Previous trials have raised the possibility that survival may be increased in patients with amyloidosis, if chemotherapy and stem-cell transplantation is performed after a heart transplant.

We plan to review data of patients with amyloidosis and heart failure who were being evaluated for a heart transplant.

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients with amyloidosis
  • NYHA class III or IV heart failure
  • Patients undergoing heart transplant evaluation
  • Patients less than 18 years of age

Exclusion criteria

  • Patients who have unstable pulse and blood pressure

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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