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Characterization of Cardiac Electrophysiological Effects of Autonomic Neuromodulation

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University of Pennsylvania

Status and phase

Enrolling
Early Phase 1

Conditions

Ventricular Tachycardia

Treatments

Drug: Stellate Ganglion Block

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

Prospective cohort study evaluating the electrophysiologic and biochemical effects of stellate ganglion block in patients with ventricular tachycardia.

Enrollment

20 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Planned catheter based VT ablation
  • Age at least 18 years

Exclusion criteria

  • Pregnancy
  • Contraindication to SGB or VT ablation
  • Hypersensitivity of local anesthetic of amide type
  • Hemodynamic instability during the procedure prior to the study protocol

Trial design

Primary purpose

Basic Science

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

20 participants in 1 patient group

Stellate ganglion block
Experimental group
Description:
All subjects will undergo stellate ganglion block during their VT ablation procedure
Treatment:
Drug: Stellate Ganglion Block

Trial contacts and locations

1

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Central trial contact

Timothy Markman, MD

Data sourced from clinicaltrials.gov

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