Cryopreserved Hair Follicles for Disease and Cell Replacement

Acorn Biolabs

Status: Enrolling

Conditions: Injury Traumatic; Diabetes Mellitus; Sport Injury

Study type: Observational

Funder types: Industry

Identifiers

NCT06764719

Company Sponsored (Other Identifier)

24-003

Details and patient eligibility

About

To explore the application of cells expanded from plucked hair follicles after collection, transport, and cryopreservation, in disease modeling and cell-based therapies.

Full description

Hair Follicles collected and transported in Acorn's proprietary transport media can serve has therapeutic starting materials for future cell-based therapeutics. This study is to characterize primary cell outgrowth, functional stem cell generation and induced pluripotent stem cell line(s) from primary outgrowth(s) as well as evaluate and characterize differentiation of stem cell lines into functional cell types required for various disease states and cell-based application(s).

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Gender: Male or Female.
• Age: ≥18 and ≤80 years.
• Language proficiency: Able to read and understand English.
• Informed consent: Willing to provide written, informed consent to participate in all study activities.

Exclusion criteria

• Scalp/Hair Disorders: Subjects diagnosed with active scalp infections or inflammatory skin conditions.
• Systemic Conditions: Subjects with chronic illnesses, such as autoimmune diseases or diabetes, that may impact scalp health or wound healing.
• Medications: Subjects on immunosuppressants, steroids, or other medications associated with hair loss.

Trial design

100 participants in 1 patient group

Hair Follicle Donors

Description:

Healthy individuals, aged 18-80, who will have hair follicles collected