Characterization of Local and Systemic Bone Markers in Diabetes Patients With Charcot Osteoarthropathy

Bispebjerg Hospital

Status: Completed

Conditions: Diabetes Complications; Diabetes Mellitus; Arthropathy, Neurogenic

Treatments: Procedure: Blood sample measurements

Study type: Observational

Funder types: Other

Identifiers

NCT02386579

H-1-2014-069

Details and patient eligibility

About

The study is designed to investigate biomarkers related to bone turnover in diabetics with charcot foot. This is done by measuring local blood samples in the feet, and systemically in a vene and an artery. Measurements are done before and after cooling the feet in icewater to lower the bloodflow.

Patients will be compared with healthy diabetic controls.

Enrollment: 5 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diabetes mellitus type 1 or 2
• Charcot foot diagnosed with x-ray, scintigraphy or clinical review by a specialist

Exclusion criteria

• Osteoporosis
• Anti-osteoporotic treatment
• Lower extremity amputation
• Lower extremity infection

Trial design

5 participants in 1 patient group

Diabetics with Charcot foot

Treatment:

Procedure: Blood sample measurements