Characterization of the Autofluorescence of Healthy and Pathological Tissues of Vocal Cords (FLUOROCORD)

Centre Hospitalier Universitaire de Besancon

Status: Completed

Conditions: Laryngeal Neoplasms

Study type: Observational

Funder types: Other

Identifiers

NCT03585075

P/2014/216

Details and patient eligibility

About

The aim of this clinical trial is to provide information about autofluorescence of pathological versus healthy vocal folds tissues.

Experimentations are performed on vocal folds biopsies obtained from patients, surgered at ENT department, university hospital of Besançon. After being extracted, samples of vocal folds are submitted to excitations at 365 nm, 405 nm and 450 nm; light spectral absorptions are measured, and results are compared to reference anatomopathology.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patient view in ENT department, presenting vocal fold lesion that necessitate biopsy
• patient informed and with non opposition

Exclusion criteria

• small (<1mm) and/or brittle sample
• Patients in emergency situations, pregnant or nursing mothers, persons deprived of their liberty, minors or protected adults.