Characterization of the Cardiac Reinnervation of Patients With Transposition of the Great Arteries Long After Repair With the Arterial Switch Operation. Correlation With Electrocardiographic and Exercise Test Parameters

Vall d'Hebron University Hospital (HUVH)

Status: Completed

Conditions: Transposition of the Great Arteries; Congenital Heart Defect; Congenital Heart Disease

Treatments: Other: Non intervention

Study type: Observational

Funder types: Other

Identifiers

NCT03469843

PR(AMI)126/2015

Details and patient eligibility

About

Cardiac denervation is inherent to the arterial switch (ASO) technique for the repair of transposition of the great arteries (TGA) and the long term reinnervation process has not been studied. We sought to describe the reinnervation status of adult patients long after the ASO, to identify areas of myocardial perfusion/innervation mismatch and to assess the relation of innervation status and exercise capacity.

Full description

Cardiac denervation is inherent to the arterial switch (ASO) technique for the repair of transposition of the great arteries (TGA) and the long term reinnervation process has not been studied. We sought to describe the reinnervation status of adult patients long after the ASO, to identify areas of myocardial perfusion/innervation mismatch and to assess the relation of innervation status and exercise capacity.

Enrollment: 25 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with transposition of the great arteries repaired with the arterial switch.
• Patients aged of more than 18 years-old.

Exclusion criteria

• Pregnancy or breast-feeding.
• Denial of informed consent.

Trial design

25 participants in 1 patient group

Patients

Description:

patients with transposition of the great arteries long after repair with the arterial switch operation

Treatment:

Other: Non intervention