Characterization of the Nutritional Status in the Patient With Liver Cirrhosis

Majadahonda Iron Gate University

Status: Completed

Conditions: Sarcopenia

Treatments: Dietary Supplement: Branched chain amino acids (BRCA)

Study type: Interventional

Funder types: Other

Identifiers

NCT04073693

11.17

Details and patient eligibility

About

In the subgroup of patients with sarcopenia, regardless of their body mass index, we want to verify the real impact of nutritional supplements with branched chain amino acids on the standard treatment based on nutritional intervention and physical exercise.

Enrollment: 32 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Cirrhotic patients with sarcopenia in abdominal CT.

Exclusion criteria

• chronic renal failure or being on hemodialysis
• active hepatitis B or C virus infection
• active alcohol abuse
• coinfection with human immunodeficiency virus
• renal or previous liver transplantation
• history of neoplasia requiring chemotherapy or radiotherapy
• hepatocellular carcinoma outside of Milan criteria
• TIPs
• unwillingness to participate in the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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32 participants in 2 patient groups, including a placebo group

BRCA

Active Comparator group

Description:

They were in treatment with BRCA and standard treatment based on nutritional intervention and physical exercise.

Treatment:

Dietary Supplement: Branched chain amino acids (BRCA)

Placebo

Placebo Comparator group

Description:

They only were on standard treatment based on nutritional intervention and physical exercise.

Treatment:

Dietary Supplement: Branched chain amino acids (BRCA)