Characterization of White Blood Cells Sub-populations From Multiple Sclerosis Patients.

Bioimmunate

Status: Unknown

Conditions: Multiple Sclerosis

Treatments: Other: CSF Sampling; Other: Blood Sampling

Study type: Observational

Funder types: Industry

Identifiers

NCT03486665

BIT-001

Details and patient eligibility

About

Multiple sclerosis (MS) is a chronic progressive neurological autoimmune disease, that gradually affects patient's quality of life. There are about 2.5 millions patients world wide, with an increasing cost Burdon. Up to date, it remains unclear who are the exact cells to initiate the disease. During the disease, the repertoire of cells expands and undergoes changes. The purpose of this study is to characterize those changes.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with diagnosis of MS according to the revised criteria of McDonald or healthy volunteers
• Ability to provide written informed consent.

Exclusion criteria

• Active malignant disease

Trial design

60 participants in 3 patient groups

Diagnosed with Multiple Sclerosis

Description:

Patients previously diagnosed with Multiple Sclerosis

Treatment:

Other: Blood Sampling

Newly Diagnosed with Multiple Sclerosis

Description:

Patients diagnosed for the first time with Multiple Sclerosis and hospitalized

Treatment:

Other: CSF Sampling

Other: Blood Sampling

Healthy Volunteers

Description:

Health volunteers who do not have an autoimmune diseases, including Multiple Sclerosis

Treatment:

Other: Blood Sampling