Characterizing the Association Between Preoperative Depressive Symptoms and Opioid Use/Misuse After Surgery

Stanford University

Status: Completed

Conditions: Opioid Use

Study type: Observational

Funder types: Other

Identifiers

NCT05412342

43163

Details and patient eligibility

About

This observational study aims to characterize the relationship between preoperative depressive symptoms and opioid use/ misuse after surgery using a perioperative learning health care system. We will follow a prospective cohort of patients undergoing elective surgery.

Enrollment: 718 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age 18+
2. Planning to undergo surgery
3. English speaking
4. Ability and willingness to complete questionnaires and assessments

Exclusion criteria

1. Any conditions causing inability to complete assessments (education, cognitive ability, mental status, medical status)
2. Known Pregnancy
3. Elevated Suicidality
4. Enrollment in a conflicting perioperative trial

Trial design

718 participants in 1 patient group

Patients undergoing elective operations

Description:

We will follow a prospective cohort of 558 patients, undergoing any elective surgery at Stanford Hospital. Subjects will undergo baseline and longitudinal testing via a (including NIH Patient-Reported Outcomes Measurement Information System- PROMIS measures of emotional distress). After surgery, participants will report weekly changes in opioid use, pain, and adverse events; and monthly changes in opioid misuse for 1 year.