Childhood Body Composition and Brain Structure and Function

Arkansas Children's Hospital Research Institute

Status: Completed

Conditions: Healthy

Study type: Observational

Funder types: Other

Identifiers

NCT01822054

133540

Details and patient eligibility

About

The specific aim of this research project is to use MRI methods to evaluate and compare brain structure and function in normal weight and obese children age 8-10 years.

Enrollment: 27 patients

Sex: All

Ages: 8 to 10 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy normal weight or obese children
• Parental report of full-term gestation
• Parental report of birth weight between 5th-95th percentiles
• Parental report of breastfeeding or cow's milk formula fed during infancy
• Right hand dominance

Exclusion criteria

• Maternal diabetes
• Maternal alcohol, tobacco or drug use during pregnancy
• Chronic sleep disorder
• History of psychological or psychiatric diagnosis
• History of neurological impairment or injury
• Surgical implant or other foreign object in the body which may be a MRI safety concern
• Dental work which may cause artifacts in MRI
• Claustrophobia
• High likelihood of inability to tolerate loud noise from the MRI scanner

Trial design

27 participants in 2 patient groups

Normal weight

Obese