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China Atopic Dermatitis Registry Study

P

Peking University

Status

Enrolling

Conditions

Dermatitis, Atopic

Treatments

Other: No intervention

Study type

Observational

Funder types

Other

Identifiers

NCT05023668
SGZ-2020-12888

Details and patient eligibility

About

This regestry study is aimed to characterize the medical care and drug treatment under real-life conditions among Chinese patients with moderate to severe Atopic Dermatitis who are not well controlled by topical therapies.

Full description

Atopic dermatitis (AD) is a chronic recurrent inflammatory skin disease, resulting in itchy, red, and skin lesion. A survey conducted in 2014 in 39 tertiary hospitals of 15 provinces in mainland China has shown that the incidence of AD in outpatients (7.8%) has been raised in recent years.

Among topical therapy of AD, corticosteroids are first line therapy. In patients with extensive and severe dermatitis, topical therapy may be insufficient. Such patients may require the addition of either oral corticosteroid or systemic immunosuppressive therapy and even phototherapy. There is no clear recommendation treatment for each kind of patients with different severity yet and there are still huge unmet medical needs for treatment. There is not clear recommendation grade for these therapy in Chinese AD guideline and no published data to demonstrate current treatment situation in real clinical practise.

The goal of clinical registry study is to document the use and effectiveness of therapeutic interventions under real-life conditions. This study will help understand the clinical characteristics, treatment utilization, treatment patterns, as well as disease-related outcomes and cost among AD patients in China.

Enrollment

10,000 estimated patients

Sex

All

Ages

12+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age≥12;
  • AD according to Williams diagnosis criteria (see Appendix 1);
  • Moderate to severe AD that inadequately controlled by topical therapy
  • Moderate-to-severe: SCORAD score≥25; or
  • Inadequately controlled by topic therapies: Determined by physicians.

Exclusion criteria

  • No.

Trial design

10,000 participants in 1 patient group

Chinese moderate to severe atopic dermatitis patients not controlled by topical therapy
Description:
Chinese moderate to severe atopic dermatitis patients not controlled by topical therapy
Treatment:
Other: No intervention

Trial contacts and locations

1

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Central trial contact

Jianzhong Zhang; Ping Liu

Data sourced from clinicaltrials.gov

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