China Valve Registry Study-1 (CHIVAS-1)

Fudan University

Status: Unknown

Conditions: Heart Valve Diseases; Aortic Valve Stenosis; Aortic Valve Disease; Aortic Valve Insufficiency

Study type: Observational

Funder types: Other

Identifiers

NCT02623907

CHIVAS2015

Details and patient eligibility

About

With the aging of Chinese population, degenerative valvular disease is becoming more and more frequent, which has brought a heavy burden to our society. Taking aortic stenosis (AS) as an example, the incidence of AS in population over the age of 65 are about 2%, and in population above the age of 85 can be amounted to 4-8%, in the Western country. Since the invention of transcatheter aortic valve replacement (TAVR),aortic valve disease (AVD),including AS and aortic regurgitation (AR), has attracted more and more attention. To date, there are few data about the prevalence of AVD in China. The characteristics and prognosis of AVD in China are still unknown. Therefore, the investigators design a prospective, observational cohort study to investigate characteristics, treatments and prognosis of AVD in Chinese elderly population. The results of the study will provide a basis for the future national health policy for prevention and treatment of AVD in the elderly.

Enrollment: 2,000 estimated patients

Sex: All

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Severe AS or AR indicated by echocardiography ;
• 60 years old or older.

Exclusion criteria

• Having both Severe AR and Severe AS;
• Having underwent surgical or transcatheter treatment for AVD;
• Non-degenerative AVD.

Trial design

2,000 participants in 2 patient groups

AS group

Description:

Severe AS patients, without severe AR

AR

Description:

Severe AR patients, without severe AS