Chinese and Western Medicine Treatment of Fever Associated With Bleeding Symptoms

Guangzhou Medical University

Status and phase: Unknown; Phase 2

Conditions: Dengue Fever; Viral Haemorrhagic Fever

Treatments: Drug: Western Medicine; Drug: TCM and Western Medicine

Study type: Interventional

Funder types: Other

Identifiers

NCT01973855

2012ZX10004301-003

Details and patient eligibility

About

To meet eligibility criteria, this study and informed consent of the syndrome of fever associated with bleeding of infectious diseases, severe patients to carry out multicenter, practical randomized controlled clinical research, to compare the curative effect of western medicine, combining Chinese and western medicine treatment, and security, and pathogenesis of TCM and syndrome, severe immune related factor and syndrome type of traditional Chinese medicine, Chinese medicine prescriptions mechanism research.

Full description

Randomized method: using large sample, central randomized, parallel comparison of Chinese and western medicine and western medicine group.

Enrollment: 300 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Viral diseases, such as dengue fever, kidney of hemorrhagic fever, such as xinjiang hemorrhagic fever; Or clinical has fever associated with bleeding as the main performance, and confirmed as the new emergent infectious diseases

Exclusion criteria

• Diagnosed with flu, hand, foot and mouth disease, viral hepatitis (except the carrier), liver cirrhosis after hepatitis, AIDS, rabies, encephalitis, polio, measles, German measles, chickenpox, herpes, infectious mononucleosis, infectious atypical pneumonia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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300 participants in 2 patient groups, including a placebo group

TCM and Western Medicine

Experimental group

Description:

TCM and Western Medicine:First Infectious diseases soup recipe,every time a dose,Two times a day;Ribavirin 10-15mg per kg every time Western Medicine：Ribavirin 10-15mg per kg every time

Treatment:

Drug: TCM and Western Medicine

Drug: Western Medicine

Western Medicine

Placebo Comparator group

Description:

Western Medicine：Ribavirin 10-15mg per kg every time

Treatment:

Drug: TCM and Western Medicine