Chiropractic T Cell Study

University of British Columbia

Status: Completed

Conditions: Intervention; Waitlist Control

Treatments: Procedure: full spine corrective protocol

Study type: Interventional

Funder types: Other

Identifiers

NCT05412602

H21-00643

Details and patient eligibility

About

Some studies suggest that specific chiropractic care (techniques known as "spinal manipulation therapy") can have benefits to the immune system but studies are scarce, sample sizes small, and methodology and analyses often not of the highest scientific standards. The investigators will example how 36 sessions of chiropractic care over 9-12 weeks can impact immune cell function using a randomized clinical trial design.

Enrollment: 38 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Must be between the ages of 18-70.
• Must exhibit vertebral subluxation as measured by a misalignment between one or more vertebrae in relation to normal spinal alignment.
• Have not been sick for the past 3 weeks (immune function).
• Non-smoker.
• Must be able to fast for 10-12 hours.

Exclusion criteria

• To have had a chiropractic intervention within the past 6 months.
• To have a condition that may limit the ability to apply a high velocity, low amplitude (HVLA) thrust to the spine such as but not limited to ligament damage, reduced bone density, or other factors that weaken the body's ability to withstand reasonable care (bone cancer, fractures, osteoporosis, etc.)
• To have excessive scoliotic curvature of the spine (> 30º) as measured by identifying the first vertebrae, and the most laterally displaced vertebrae that exhibits tilt below it.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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38 participants in 2 patient groups

Intervention

Experimental group

Description:

experimental group will receive 36 chiropractic treatments designed to correct vertebral subluxation over \~12 weeks

Treatment:

Procedure: full spine corrective protocol

waitlist control

No Intervention group

Description:

waitlist control will receive no chiropractic interventions and will be reminded that to successfully complete their condition, they do not seek alternative chiropractic treatments